The rumors apear to be true, Human Target will have a season two! The thirteen episode run will start in the fall of 2010 on Fox. However we can't confirm as of yet the Matthew Miller as showrunner rumor, so far the official release sent to us by Warner Brothers lists the following:

Product #: TBAHT2 Genre(s): adventure, drama, action Season: 2 Season Premiere: Fall 2010 Countries of Origin: U.S. Language: English Program Length (min): 60 Network(s): FOX-Primary Production Company(s): Bonanza Productions Inc. in association with Wonderland Sound and Vision, DC Comics and Warner Bros. Television Production Company: Warner Bros. Television, DC Comics, Wonderland Sound and Vision Total Number of Episodes: 13 Start Year: 2010 End Year: 2011